Liberal or restrictive dilemma—that’s a CLASSIC!

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Liberal or Restrictive Transfusion after Cardiac Surgery.

BACKGROUND Whether a restrictive threshold for hemoglobin level in red-cell transfusions, as compared with a liberal threshold, reduces postoperative morbidity and health care costs after cardiac surgery is uncertain. METHODS We conducted a multicenter, parallel-group trial in which patients older than 16 years of age who were undergoing nonemergency cardiac surgery were recruited from 17 cen...

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Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study.

BACKGROUND Evidence-based guidelines on optimal perioperative fluid management have not been established, and recent randomized trials in major abdominal surgery suggest that large amounts of fluid may increase morbidity and hospital stay. However, no information is available on detailed functional outcomes or with fast-track surgery. Therefore, we investigated the effects of two regimens of in...

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Restrictive versus liberal transfusion strategies for red blood cell transfusion after hip or knee surgery

BACKGROUND Red blood cell (RBC) transfusions are commonly used in surgical patients, but accompanied by many risks such as metabolic derangement, and allergic and febrile reactions. Indications for transfusion in patients after hip or knee surgery have not been definitively evaluated and remain controversial. We performed a meta-analysis to compare the benefits and harms of restrictive versus l...

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Liberal or restrictive transfusion in high-risk patients after hip surgery.

BACKGROUND The hemoglobin threshold at which postoperative red-cell transfusion is warranted is controversial. We conducted a randomized trial to determine whether a higher threshold for blood transfusion would improve recovery in patients who had undergone surgery for hip fracture. METHODS We enrolled 2016 patients who were 50 years of age or older, who had either a history of or risk factor...

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Restrictive and liberal fluid administration in major abdominal surgery

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ژورنال

عنوان ژورنال: Annals of Translational Medicine

سال: 2017

ISSN: 2305-5839,2305-5847

DOI: 10.21037/atm.2017.03.25